Is it possible to kill an ant colony queen anymore?

I can't seem to find any products on the net that will kill a colony of ants by, for example, tricking the ants into bringing the poison to the queen ant. They all just attract ants in large numbers to the bait and then they die shortly afterward. This is clearly a temporary solution, as the queen can just make more ants. Also, I've read that sometimes, the ants actually learn to avoid the bait and will go to some lengths to avoid even crawling near it.